RESUMO
La yoduria o eliminación urinaria de yodo (EUI) es un método efectivo para detectar el déficit en su ingesta. En 121 embarazadas se midió yoduria en dos muestras (matutina y vespertina) con el método turbidimétrico modificado por Pino. Se consideró normal una EUI =150 ug/l. En las mujeres con EUI<100ug/l se investigó la función tiroidea. De 121 embarazadas la yoduria fue normal en 75, en las que la yoduria matinal no fue diferente a la vespertina (matutina: 305.2 ± 7.0 vs vespertina: 319.2 ± 8.8; NS). No hubo diferencia entre las yodurias de los diversos trimestres. En 46 embarazadas (36.9 por ciento) la yoduria fue baja sin diferencias entre la matutina y vespertina (matutina: 88.12 ± 5.07 µg/l vs 88.7 ± 6.2 µg/l; NS), al igual que entre las yodurias matutinas y vespertinas en los tres trimestres de embarazo. De las embarazadas con yodurias <100ug/l, el 45 por ciento presentó alteraciones de la función tiroidea. No hubo diferencias significativas respecto a la edad entre las embarazadas con baja y normal EUI. La determinación de yoduria matutina y vespertina permitió detectar un mayor número de embarazadas con baja ingesta de yodo y orientó para la búsqueda de disfunción tiroidea que no se hubiera detectado por no contar nuestra Provincia con un Programa de screening para hipotiroidismo gestacional.
The urinary iodine excretion (UIE) assay is an effective method to detect reduced iodine intake. UIE was measured in two different samples (morning and evening) from 121 pregnant women, with a turbid-metric method modified by Pino (normal value =150 ug/l). Furthermore, thyroid function was evaluated in pregnant women with UIE <100 ug/l. From 121 pregnant women, the UIE was normal in 75 with similar morning and evening samples (morning: 305.2 ± 7.0; evening: 319.2 ± 8.8; p: NS). The UIE did no showed differences in different trimesters and in morning and evening samples. The UIE was low in 46 women (36.9 percent), without significant differences between morning and evening (morning: 88.12 ± 5.07 µg/l; evening: 88.7 ± 6.2 µg/l; p: NS). Normal or low UIE were not influenced by the age of pregnant women and 45 percent of pregnant women with UIE <100ug/l showed impaired thyroid function. Morning and evening study of UIE allowed us to detect a higher number of pregnant women with low iodine intake. This study let us to find thyroid function abnormalities likes a screening method, because in our state there is not a public screening program for gestational hypothyroidism.
Assuntos
Humanos , Feminino , Gravidez , Testes de Função Renal/métodos , Doenças da Glândula Tireoide , Iodo/administração & dosagem , Saúde PúblicaRESUMO
The urinary iodine excretion (UIE) assay is an effective method to detect reduced iodine intake. UIE was measured in two different samples (morning and evening) from 121 pregnant women, with a turbid-metric method modified by Pino (normal value =150 ugl/1). Furthermore, thyroid function was evaluated in pregnant women with UIE <100 ug/l. From 121 pregnant women, the UIE was normal in 75 with similar morning and evening samples (morning: 305.2 +/- 7.0; evening: 319.2 +/- 8.8; p: NS). The UIE did no showed differences in different trimesters and in morning and evening samples. The UIE was low in 46 women (36.9%), without significant differences between morning and evening (morning: 88.12 +/- 5.07 microg/l; evening: 88.7 +/- 6.2 microg/l; p: NS). Normal or low UIE were not influenced by the age of pregnant women and 45% of pregnant women with UIE < 100 ug/l showed impaired thyroid function. Morning and evening study of UIE allowed us to detect a higher number of pregnant women with low iodine intake. This study let us to find thyroid function abnormalities likes a screening method, because in our state there is not a public screening program for gestational hypothyroidism.
